Microbes, including bacteria, archaea, and single celled eukaryotes, represent the most abundant and diverse group of organisms on Earth. Many bacteria and fungi have evolved complex associations with eukaryotic, multicellular organisms. These interactions range from beneficial symbiotic relationships to those that are responsible for diseases, and have helped biologists to better understand the relationship between both partners. In this course, we will discuss seminal research and current open questions exploring non-human, host-microbe interactions. Examples will span kingdoms and ecosystems, including interactions between bobtail squid and bioluminescent microbial colonizers, termites and their bacterial endosymbionts, nitrogen-fixing bacteria and legumes. We will explore a variety of different strategies used by microbial pathogens of plants and mammals to mimic host functions or manipulate host responses. Students will gain an understanding of both the molecular mechanisms and key components underlying host-microbe interactions and the biological theories that have emerged from these studies, with a focus on reading, discussing, and critiquing primary literature.

Units: 1

Max Enrollment: 12

Prerequisites: One of (BISC 209, BIOC 219/BISC 219, BIOC 220/BISC 220) or permission of the instructor.

Distribution Requirements: NPS - Natural and Physical Sciences

Typical Periods Offered: Fall

Semesters Offered this Academic Year: Spring

Notes: